The Ultimate Gainesville Weekend Itinerary: What To Do
Gainesville, FL: What to Do, See & Where to Stay

Your complete guide to exploring Gainesville, FL in just three days — with the perfect place to stay
Planning a weekend trip to Gainesville, Florida? Whether you’re visiting the University of Florida, soaking up the sunshine in local springs, or just looking for a relaxed Southern getaway, Gainesville offers the perfect blend of outdoor adventure, arts, history, and small-town charm. And with StayGainesville’s vacation rentals, you’ll feel right at home no matter your style or budget.
We’ve created the ultimate 3-day Gainesville itinerary to help you make the most of your time — including where to eat, what to explore, and the best place to stay.
Day 1: Explore Downtown & Discover Local Flavor
✅ Check In to Your StayGainesville Home
Start your weekend by checking into a stylish and fully furnished StayGainesville rental. Whether you’re looking for a historic inn, a pet-friendly bungalow, or a modern condo near UF, StayGainesville offers a range of options to fit couples, families, and groups.
Pro tip: Book direct on StayGainesville.com and use code DIRECT10 to save 10%.
Our properties are centrally located so with some you can leave the car behind and enjoy Gainesville on foot.
☕ Coffee & Culture
Start your afternoon with a caffeine fix from Wyatt’s Coffee or Cymplify, two local favorites offering top-tier espresso and Gainesville charm. If you're in the mood for something sweet, stop by Doux Bites or Krispy Kreme.
🎭 Downtown Stroll & The Hippodrome
Next, take a walk through Historic Downtown Gainesville. Stop in the local shops, art galleries, and check out the Hippodrome Theatre, a beautifully restored building that hosts plays, films, and cultural events.
🍽 Dinner at The Top or Embers
Dinner is best spent at The Top, a hip downtown restaurant known for its eclectic menu and funky vibe. Looking for upscale dining? Embers Wood Grill offers craft cocktails and locally sourced dishes in a warm, modern space.
🌙 Nightcap or Nature
Wrap up your night with a drink at Cry Baby’s, Loosey’s, or a sunset stroll around Depot Park, where you can catch live music or seasonal events. If you’re traveling with kids, the park also features an interactive splash pad and playground.
Day 2: Outdoor Adventures & Iconic Gainesville Eats
🏞 Morning: Florida's Natural Beauty
Gainesville is known for its springs, trails, and wild beauty. Take a short drive to:
Ichetucknee Springs – crystal-clear tubing and kayaking
Sweetwater Wetlands Park – scenic boardwalks and birdwatching
Kanapaha Botanical Gardens – a peaceful garden escape
Gainesville-Hawthorne Trail – ideal for cycling or walking
Don’t forget your sunscreen and water shoes!
🍕 Afternoon: Satchel’s Pizza & Local Shopping
After working up an appetite, head to Satchel’s Pizza, a local institution famous for its quirky decor and deep-dish pies. Sit in the old van if it’s available, and check out the attached art store, Lightnin’ Salvage.
Looking for unique finds? Stop by Thornebrook Village or The Repurpose Project for one-of-a-kind local gifts and antiques.
🐊 Evening: Gator Game or Live Music
If it’s a football weekend, you’ll want to be near The Swamp. Whether you have tickets or not, the energy around Ben Hill Griffin Stadium is electric. Many StayGainesville homes are within walking distance, so you won’t have to fight for parking.
Not into sports? Enjoy dinner and live jazz at Blue Gill Quality Food, or check the Visit Gainesville calendar for local concerts and themed nights.
Day 3: Science, Butterflies & Brunch
🦋 Butterfly Rainforest & Museums
Start your final day with a visit to the Florida Museum of Natural History and its magical Butterfly Rainforest — a tropical oasis of free-flying butterflies, waterfalls, and exotic plants.
Also on-site: the Harn Museum of Art, a free museum showcasing an impressive collection of contemporary and global art.
🥞 Brunch It Up
Don’t leave Gainesville without brunch! Local favorites include:
Superette – globally inspired with vegetarian options
43rd Street Deli – classic Southern breakfast
Curia on the Drag – funky outdoor café with vegan eats and vintage finds
🚗 Wrap Up with a Stroll or Shopping
Before heading home, take a relaxing walk through Paynes Prairie Preserve or visit the Haile Village Center for a final bite or coffee. If you're in town on a Saturday, check out the Union Street Farmers Market or Haile Farmers Market for local produce and live music.
🏡 Where to Stay: StayGainesville
Gainesville has its fair share of hotels, but StayGainesville offers the comfort, privacy, and personality you won’t find anywhere else.
Choose from:
Downtown historic homes with porches, gardens, and fireplaces
Pet-friendly bungalows near trails and dog parks
Whole-house rentals for weddings, events, and large gatherings
Condos near UF and Shands for parents, students, and medical travelers
Each home is carefully curated and professionally cleaned, with fully stocked kitchens, Wi-Fi, and smart locks for easy self-check-in.
Final Thoughts
Whether you're in Gainesville for a weekend getaway, a big game, or just passing through, this vibrant college town has plenty to offer. With world-class nature, fantastic food, and friendly locals, it’s the perfect blend of adventure and Southern charm.
And when you stay with StayGainesville, you’re not just booking a place — you're experiencing Gainesville like a local.
💬 Ready to plan your visit?
Explore our listings at www.staygainesville.com or call us for help planning your stay.
Frequently Asked Questions (FAQs) About Visiting Gainesville, FL
What’s the best area to stay in Gainesville for a weekend trip?
If you want to be close to dining, parks, and nightlife, downtown Gainesville is ideal. StayGainesville offers centrally located vacation rentals within walking distance to Depot Park, the Hippodrome, and local favorites like The Top.
Are there vacation rentals near the University of Florida?
Yes! Many of StayGainesville’s properties are walking distance or a short drive from UF’s campus and Ben Hill Griffin Stadium — perfect for Gator game weekends or campus visits.
What are the top things to do in Gainesville in a weekend?
Highlights include the Butterfly Rainforest, Depot Park, Ichetucknee Springs, Satchel’s Pizza, and catching a show or game at the University of Florida.
Is Gainesville family-friendly?
Absolutely. With attractions like Sweetwater Wetlands, the Florida Museum of Natural History, and kid-friendly dining, Gainesville is a great destination for families.
Can I bring my dog to a StayGainesville rental?
Yes — several of our vacation homes are pet-friendly, with fenced yards and easy access to parks and trails.
When is the best time to visit Gainesville, FL?
Spring and fall offer mild weather, football season excitement, and vibrant events. Summers are hot but great for visiting local springs.